‘Yes, that is definitely about correct. I seek out a physical comprehension of Organic techniques in a very bottom-up way. I believe you could potentially distinguish three traces of exploration in my group in the intervening time. The very first worries chromosome composition: How can you get yourself a metre-extensive DNA polymer folded and organised in such a microscopic cell? We have now developed visualisation methods that let us to check how, for instance, SMC proteins loop DNA (video clip on Youtube) in an effort to Establish up chromosomes.
Our team experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that will autonomously divide. Our primary interest lies in mobile division, chromatin construction, and spatial Handle.
Multicolor imaging in the bacterial nucleoid and cell division proteins with blue, orange, and close to-infrared fluorescent proteins
Since 2000, Dekker has shifted the key aim of his function in direction of biophysics where by he scientific studies the Houses of one biomolecules and cells using the resources of nanotechnology. This modification of field was driven by his fascination to the amazing performing of biological molecular structures, along with with the very long-time period perspective that a lot of exciting discoveries is often envisioned in this field.[5] Present lines of analysis in his biophysics team are from the parts of:[six]
This yielded a breakthrough. In just just a few months, we were being capable to measure transport through someone one-walled carbon nanotube. Determined by low-temperature experiments by an excellent PhD student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technologies having an active exploration lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Our exploration ranges with the biophysics of DNA to artificial cells and outside of. Please take a look down below within the spectrum of our latest initiatives.
A lot of linked developments adopted, wherever our team recognized distinctive transistor variants which include one-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into small evidence-of-basic principle electronic circuits.
He also observed time to write down various books, send out Virtually forty thousand tweets and guide a successful investigation team at Delft University of Technological know-how. ‘It doesn’t really feel like get the job done’, he says. ‘I’m just terribly curious.’
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At the moment, we also realized that it ought to be probable to employ only one semiconducting carbon nanotube to help make a transistor — and we established out to make it. We stretched personal semiconducting nanotubes throughout metallic electrodes and utilised the underlying silicon substrate as being a gate electrode, establishing The essential 3-terminal format of a area-effect transistor (Fig.
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‘I am pushed by speculate and thoughts. On a material level I locate solutions in physics, but I knowledge my deepest pleasure with God. That religion also drives my science And exactly https://www.ceesdekker.net how I contend with people.